ZENGLAD - IV

(Mannitol & Glycerin IV Infusion)

Product Overview

ZENGLAD-IV is an intravenous solution combining Mannitol and Glycerin, both recognized for their osmotic diuretic properties. Designed to reduce intracranial pressure (ICP), lower intraocular pressure, and support acute renal management, ZENGLAD-IV offers healthcare professionals a reliable option for managing fluid shifts and preventing further complications in critical care settings.

Key Ingredient & Its Benefits

1. Mannitol

   • Osmotic Diuretic Action: Draws excess fluid out of tissues and into the bloodstream, promoting diuresis.

   • Reduces Intracranial Pressure: Widely used to decrease cerebral edema in neurosurgical or neurological conditions.

   • Protects Renal Function: Can aid in maintaining urine output during acute kidney injury or other renal-compromised states.

2. Glycerin

   • Additional Osmotic Support: Enhances Mannitol’s diuretic effect by increasing fluid excretion.

   • Gentle on Tissues: Generally well-tolerated, contributing to smooth fluid management without harsh irritation.

   • Versatile Clinical Uses: Can also help lower intraocular pressure, making it valuable in ophthalmic care.

How It Works

1. Osmotic Gradient Creation

   • Mannitol and Glycerin pull fluid from brain tissue, eyes, or other edematous areas into the vascular compartment.

2. Increased Urine Output

   • The fluid drawn into the bloodstream is then excreted via the kidneys, reducing fluid overload and edema.

3. Neuroprotection & Renal Support

   • By lowering intracranial pressure and ensuring adequate diuresis, ZENGLAD-IV helps prevent further tissue damage and supports renal perfusion.

Indications

• ZENGLAD-IV is commonly used in:

  • Elevated Intracranial Pressure (e.g., cerebral edema)

  • Acute Glaucoma or Raised Intraocular Pressure

  • Renal Protection in acute kidney injury (as part of a broader treatment plan)

  • Forced Diuresis in certain toxic ingestions (under specialist guidance)

  Usage may vary based on the clinical scenario and physician discretion.

Recommended Usage

• Dosage: Determined by patient weight, clinical condition, and treatment goals (e.g., reducing ICP or managing acute renal issues).

• Administration: Administered intravenously under strict medical supervision, with careful monitoring of fluid balance and electrolytes.

• Rate of Infusion: Adjusted to achieve desired diuretic effect while preventing rapid shifts in fluid or electrolyte imbalances.

Important: Continuous observation of vital signs, urine output, and electrolyte levels is essential during administration.

Key Benefits

1. Rapid Osmotic Diuresis

   • Helps quickly reduce intracranial or intraocular pressure.

2. Dual-Action Formula

   • The combination of Mannitol & Glycerin provides enhanced osmotic effect, optimizing fluid removal.

3. Supports Neurological & Renal Outcomes

   • Helps prevent further damage in cases of cerebral edema and acute kidney injury.

4. Flexible Clinical Application

   • Can be used in neurocritical care, ophthalmology, and nephrology settings.

Safety & Precautions

• Monitor Electrolytes & Renal Function: Rapid fluid shifts can lead to electrolyte imbalances.

• Contraindications: Not recommended in patients with severe pulmonary congestion, active intracranial hemorrhage (unless specifically indicated), or anuria unresponsive to test doses.

• Possible Side Effects: Headache, nausea, vomiting, or dizziness—report any unusual symptoms promptly.

• Use Under Medical Supervision: Strict input-output tracking and vital sign monitoring are crucial.

Why Choose Zenglad-IV ?

• Synergistic Osmotic Action: Mannitol and Glycerin work together to efficiently reduce edema and manage fluid overload.

• Reliable Quality: Manufactured under stringent pharmaceutical standards, ensuring consistency and safety.

• Versatile Clinical Use: Suitable for neurological, renal, and ophthalmic indications.

• Focused on Patient Outcomes: Aims to improve overall prognosis in critical and acute care scenarios.

This information is for educational purposes only. Treatment decisions must be made by a qualified physician based on the patient’s condition. Do not adjust dosage without medical advice.